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Structure and function of a monocarboxylate transporter homolog specific for L-lactate
Monocarboxylate transporters play important roles in certain cancers. We have reported structures of an L-lactate-transporting solute carrier family 16 homolog with bound substrate and inhibitor. The structures show the transporter in the pharmacologically relevant outward-open conformation. Structu...
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| 出版年: | Mol Cell Oncol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6816346/ https://ncbi.nlm.nih.gov/pubmed/31692891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1646605 |
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