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Mechanistic basis of L-lactate transport in the SLC16 solute carrier family
In human and other mammalian cells, transport of L-lactate across plasma membranes is mainly catalyzed by monocarboxylate transporters (MCTs) of the SLC16 solute carrier family. MCTs play an important role in cancer metabolism and are promising targets for tumor treatment. Here, we report the crysta...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6573034/ https://ncbi.nlm.nih.gov/pubmed/31201333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10566-6 |
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