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Mechanistic basis of L-lactate transport in the SLC16 solute carrier family

In human and other mammalian cells, transport of L-lactate across plasma membranes is mainly catalyzed by monocarboxylate transporters (MCTs) of the SLC16 solute carrier family. MCTs play an important role in cancer metabolism and are promising targets for tumor treatment. Here, we report the crysta...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Bosshart, Patrick D., Kalbermatter, David, Bonetti, Sara, Fotiadis, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573034/
https://ncbi.nlm.nih.gov/pubmed/31201333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10566-6
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