Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteria

Mycobacteria share with other actinomycetes the ability to produce large quantities of triacylglycerol (TAG), which accumulate as intracytoplasmic lipid inclusions (ILI) also known as lipid droplets (LD). Mycobacterium tuberculosis (M. tb), the etiologic agent of tuberculosis, acquires fatty acids f...

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Vydáno v:Sci Rep
Hlavní autoři: Santucci, Pierre, Johansen, Matt D., Point, Vanessa, Poncin, Isabelle, Viljoen, Albertus, Cavalier, Jean-François, Kremer, Laurent, Canaan, Stéphane
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572852/
https://ncbi.nlm.nih.gov/pubmed/31209261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45164-5
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