Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteria

Mycobacteria share with other actinomycetes the ability to produce large quantities of triacylglycerol (TAG), which accumulate as intracytoplasmic lipid inclusions (ILI) also known as lipid droplets (LD). Mycobacterium tuberculosis (M. tb), the etiologic agent of tuberculosis, acquires fatty acids f...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Santucci, Pierre, Johansen, Matt D., Point, Vanessa, Poncin, Isabelle, Viljoen, Albertus, Cavalier, Jean-François, Kremer, Laurent, Canaan, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572852/
https://ncbi.nlm.nih.gov/pubmed/31209261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45164-5
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