Targeting the cell cycle in head and neck cancer by Chk1 inhibition: a novel concept of bimodal cell death

Head and neck squamous cell carcinomas (HNSCCs) coincide with poor survival rates. The lack of driver oncogenes complicates the development of targeted treatments for HNSCC. Here, we follow-up on two previous genome-wide RNA and microRNA interference screens in HNSCC to cross-examine tumor-specific...

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Udgivet i:Oncogenesis
Main Authors: van Harten, Anne M., Buijze, Marijke, van der Mast, Richard, Rooimans, Martin A., Martens-de Kemp, Sanne R., Bachas, Costa, Brink, Arjen, Stigter-van Walsum, Marijke, Wolthuis, Rob M. F., Brakenhoff, Ruud H.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572811/
https://ncbi.nlm.nih.gov/pubmed/31209198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-019-0147-x
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