Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass

INTRODUCTION: Head and neck squamous cell carcinomas (HNSCC) arise in the mucosal lining of the upper aerodigestive tract. Risk factors are exogenous carcinogen exposure, human papillomavirus (HPV) infection, and genetic predisposition such as Fanconi anemia (FA). Clinically, tumors are stratified b...

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Published in:Oral Oncol
Main Authors: van Harten, Anne M., Poell, Jos B., Buijze, Marijke, Brink, Arjen, Wells, Susanne I., Leemans, C. René, Wolthuis, Rob M.F., Brakenhoff, Ruud H.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372097/
https://ncbi.nlm.nih.gov/pubmed/31541927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2019.09.004
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