Targeting PLK1 as a novel chemopreventive approach to eradicate preneoplastic mucosal changes in the head and neck

Head and neck squamous cell carcinomas (HNSCC) and local relapses thereof develop in preneoplastic fields in the mucosal linings of the upper aerodigestive tract. These fields are characterized by tumor-associated genetic changes, are frequently dysplastic and occasionally macroscopically visible. C...

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Vydáno v:Oncotarget
Hlavní autoři: de Boer, D. Vicky, Martens-de Kemp, Sanne R., Buijze, Marijke, Stigter-van Walsum, Marijke, Bloemena, Elisabeth, Dietrich, Ralf, Leemans, C. René, van Beusechem, Victor W., Braakhuis, Boudewijn J.M., Brakenhoff, Ruud H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716703/
https://ncbi.nlm.nih.gov/pubmed/29228663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17880
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