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Targeting PLK1 as a novel chemopreventive approach to eradicate preneoplastic mucosal changes in the head and neck

Head and neck squamous cell carcinomas (HNSCC) and local relapses thereof develop in preneoplastic fields in the mucosal linings of the upper aerodigestive tract. These fields are characterized by tumor-associated genetic changes, are frequently dysplastic and occasionally macroscopically visible. C...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: de Boer, D. Vicky, Martens-de Kemp, Sanne R., Buijze, Marijke, Stigter-van Walsum, Marijke, Bloemena, Elisabeth, Dietrich, Ralf, Leemans, C. René, van Beusechem, Victor W., Braakhuis, Boudewijn J.M., Brakenhoff, Ruud H.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716703/
https://ncbi.nlm.nih.gov/pubmed/29228663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17880
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