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Systemic Design and Evaluation of Ticagrelor-Loaded Nanostructured Lipid Carriers for Enhancing Bioavailability and Antiplatelet Activity

Ticagrelor (TGL), a P2Y(12) receptor antagonist, is classified as biopharmaceutics classification system (BCS) class IV drug due to its poor solubility and permeability, resulting in low oral bioavailability. Nanostructured lipid carriers (NLC) are an efficient delivery system for the improvement of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmaceutics
Prif Awduron: Son, Gi-Ho, Na, Young-Guk, Huh, Hyun Wook, Wang, Miao, Kim, Min-Ki, Han, Min-Gu, Byeon, Jin-Ju, Lee, Hong-Ki, Cho, Cheong-Weon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572397/
https://ncbi.nlm.nih.gov/pubmed/31071977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11050222
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