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DPYD and Fluorouracil-Based Chemotherapy: Mini Review and Case Report

5-Fluorouracil remains a foundational component of chemotherapy for solid tumour malignancies. While considered a generally safe and effective chemotherapeutic, 5-fluorouracil has demonstrated severe adverse event rates of up to 30%. Understanding the pharmacokinetics of 5-fluorouracil can improve t...

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Détails bibliographiques
Publié dans:Pharmaceutics
Auteurs principaux: Wigle, Theodore J., Tsvetkova, Elena V., Welch, Stephen A., Kim, Richard B.
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572291/
https://ncbi.nlm.nih.gov/pubmed/31052357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11050199
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