Učitavanje...

Changes in the allosteric site of human liver pyruvate kinase upon activator binding include the breakage of an intersubunit cation–π bond

Human liver pyruvate kinase (hLPYK) converts phosphoenolpyruvate to pyruvate in the final step of glycolysis. hLPYK is allosterically activated by fructose-1,6-bisphosphate (Fru-1,6-BP). The allosteric site, as defined by previous structural studies, is located in domain C between the phosphate-bind...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Acta Crystallogr F Struct Biol Commun
Glavni autori: McFarlane, Jeffrey S., Ronnebaum, Trey A., Meneely, Kathleen M., Chilton, Annemarie, Fenton, Aron W., Lamb, Audrey L.
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572093/
https://ncbi.nlm.nih.gov/pubmed/31204694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X19007209
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!