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Development of a Competition-Binding Assay to Determine Binding Affinity of Molecules to Neuromelanin via Fluorescence Spectroscopy

Neuromelanin, the polymeric form of dopamine which accumulates in aging neuronal tissue, is increasingly recognized as a functional and critical component of a healthy and active adult human brain. Notorious in plant and insect literature for their ability to bind and retain amines for long periods...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Fink, Jackson, Pathak, Heather, Smith, John, Achat-Mendes, Cindy, Haining, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572089/
https://ncbi.nlm.nih.gov/pubmed/31072013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9050175
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