A Novel CXCR4-Selective High-Affinity Fluorescent Probe and Its Application in Competitive Binding Assays

[Image: see text] We recently developed a new, rapid, and specific bioassay system that employs a fluorescent probe fabricated from our discovered CXCR4-specific ligand DV1. This new probe sensitively and selectively blocks the binding of native and synthetic ligands to CXCR4 at nanomolar levels, wi...

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Hlavní autoři: Yang, Yilei, Zhang, Qinghao, Gao, Mei, Yang, Xiaohong, Huang, Ziwei, An, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144712/
https://ncbi.nlm.nih.gov/pubmed/25058910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500500h
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