Nuclear Phospho-SOD1 Protects DNA from Oxidative Stress Damage in Amyotrophic Lateral Sclerosis

We already demonstrated that in peripheral blood mononuclear cells (PBMCs) of sporadic amyotrophic lateral sclerosis (sALS) patients, superoxide dismutase 1 (SOD1) was present in an aggregated form in the cytoplasmic compartment. Here, we investigated the possible effect of soluble SOD1 decrease and...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Bordoni, Matteo, Pansarasa, Orietta, Dell’Orco, Michela, Crippa, Valeria, Gagliardi, Stella, Sproviero, Daisy, Bernuzzi, Stefano, Diamanti, Luca, Ceroni, Mauro, Tedeschi, Gabriella, Poletti, Angelo, Cereda, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572067/
https://ncbi.nlm.nih.gov/pubmed/31121901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8050729
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