Pathological Proteins Are Transported by Extracellular Vesicles of Sporadic Amyotrophic Lateral Sclerosis Patients

Amyotrophic lateral sclerosis (ALS) is a progressive adult-onset neurodegenerative disease, that affects cortical, bulbar and spinal motor neurons, and it is considered a proteinopathy, in which pathological proteins (SOD1, TDP-43, and FUS) may accumulate and interfere with neuronal functions eventu...

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Vydáno v:Front Neurosci
Hlavní autoři: Sproviero, Daisy, La Salvia, Sabrina, Giannini, Marta, Crippa, Valeria, Gagliardi, Stella, Bernuzzi, Stefano, Diamanti, Luca, Ceroni, Mauro, Pansarasa, Orietta, Poletti, Angelo, Cereda, Cristina
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060258/
https://ncbi.nlm.nih.gov/pubmed/30072868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00487
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