Current Mechanistic and Pharmacodynamic Understanding of Melanocortin-4 Receptor Activation

In this work we summarize our understanding of melanocortin 4 receptor (MC4R) pathway activation, aiming to define a safe and effective therapeutic targeting strategy for the MC4R. Delineation of cellular MC4R pathways has provided evidence for distinct MC4R signaling events characterized by unique...

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Enregistré dans:
Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Sharma, Shubh, Garfield, Alastair S., Shah, Bhavik, Kleyn, Patrick, Ichetovkin, Ilia, Moeller, Ida Hatoum, Mowrey, William R., Van der Ploeg, Lex H.T.
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572030/
https://ncbi.nlm.nih.gov/pubmed/31100979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24101892
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