Tracing the effect of the melanocortin-4 receptor pathway in obesity: study design and methodology of the TEMPO registry

Purpose: The hypothalamic melanocortin-4 receptor (MC4R) pathway, a component of the central melanocortin pathway, regulates energy balance and satiety. Rare genetic disorders of obesity may be characterized by impaired MC4R pathway signaling, which results in early-onset severe obesity and insatiab...

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Detalhes bibliográficos
Publicado no:Appl Clin Genet
Main Authors: Eneli, Ihuoma, Xu, Jinyu, Webster, Matthew, McCagg, Amy, Van Der Ploeg, Lex, Garfield, Alastair S, Estrada, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556479/
https://ncbi.nlm.nih.gov/pubmed/31239751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S199092
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