Magel2‐null mice are hyper‐responsive to setmelanotide, a melanocortin 4 receptor agonist

BACKGROUND AND PURPOSE: α‐ and β‐melanocyte‐stimulating hormones (MSH) are derived from pro‐opiomelanocortin (POMC) and are the natural agonist ligands of the melanocortin 4 receptor, a key regulator of energy homeostasis. Recent rodent and human data have implicated the MAGEL2 gene, which may regul...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Bischof, Jocelyn M, Van Der Ploeg, Lex H T, Colmers, William F, Wevrick, Rachel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978157/
https://ncbi.nlm.nih.gov/pubmed/27339818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13540
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