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Magel2‐null mice are hyper‐responsive to setmelanotide, a melanocortin 4 receptor agonist
BACKGROUND AND PURPOSE: α‐ and β‐melanocyte‐stimulating hormones (MSH) are derived from pro‐opiomelanocortin (POMC) and are the natural agonist ligands of the melanocortin 4 receptor, a key regulator of energy homeostasis. Recent rodent and human data have implicated the MAGEL2 gene, which may regul...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4978157/ https://ncbi.nlm.nih.gov/pubmed/27339818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13540 |
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