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Disulfiram (Antabuse) Activates ROS-Dependent ER Stress and Apoptosis in Oral Cavity Squamous Cell Carcinoma

A paucity of advances in the development of novel therapeutic agents for squamous cell carcinomas of the head and neck, oral cavity (OSCC) and oropharynx, has stagnated disease free survival rates over the past two decades. Although immunotherapies targeted against checkpoint inhibitors such as PD-1...

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Foilsithe in:J Clin Med
Main Authors: Shah O’Brien, Priyanka, Xi, Yue, Miller, Justin R., Brownell, Amy L., Zeng, Qinghua, Yoo, George H., Garshott, Danielle M., O’Brien, Matthew B., Galinato, Anthony E., Cai, Peter, Narula, Neha, Callaghan, Michael U., Kaufman, Randal J., Fribley, Andrew M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571807/
https://ncbi.nlm.nih.gov/pubmed/31064122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8050611
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