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Mechanisms of Disulfiram-induced Cocaine Abstinence: Antabuse and Cocaine Relapse

The anti-alcoholism drug disulfiram (Antabuse), which is an inhibitor of aldehyde dehydrogenase, induces an aversive reaction to alcohol consumption and thereby helps patients reduce alcohol intake. Recent clinical trials, initiated to investigate whether disulfiram could be used to treat individual...

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Autores principales: Gaval-Cruz, Meriem, Weinshenker, David
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Pharmacology and Experimental Therapeutics 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861803/
https://ncbi.nlm.nih.gov/pubmed/19720750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mi.9.4.6
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