Disulfiram (Antabuse) Activates ROS-Dependent ER Stress and Apoptosis in Oral Cavity Squamous Cell Carcinoma

A paucity of advances in the development of novel therapeutic agents for squamous cell carcinomas of the head and neck, oral cavity (OSCC) and oropharynx, has stagnated disease free survival rates over the past two decades. Although immunotherapies targeted against checkpoint inhibitors such as PD-1...

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Vydáno v:J Clin Med
Hlavní autoři: Shah O’Brien, Priyanka, Xi, Yue, Miller, Justin R., Brownell, Amy L., Zeng, Qinghua, Yoo, George H., Garshott, Danielle M., O’Brien, Matthew B., Galinato, Anthony E., Cai, Peter, Narula, Neha, Callaghan, Michael U., Kaufman, Randal J., Fribley, Andrew M.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571807/
https://ncbi.nlm.nih.gov/pubmed/31064122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8050611
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