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Disulfiram (Antabuse) Activates ROS-Dependent ER Stress and Apoptosis in Oral Cavity Squamous Cell Carcinoma

A paucity of advances in the development of novel therapeutic agents for squamous cell carcinomas of the head and neck, oral cavity (OSCC) and oropharynx, has stagnated disease free survival rates over the past two decades. Although immunotherapies targeted against checkpoint inhibitors such as PD-1...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Shah O’Brien, Priyanka, Xi, Yue, Miller, Justin R., Brownell, Amy L., Zeng, Qinghua, Yoo, George H., Garshott, Danielle M., O’Brien, Matthew B., Galinato, Anthony E., Cai, Peter, Narula, Neha, Callaghan, Michael U., Kaufman, Randal J., Fribley, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571807/
https://ncbi.nlm.nih.gov/pubmed/31064122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8050611
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