An UNC5C Allele Predicts Cognitive Decline and Hippocampal Atrophy in Clinically Normal Older Adults

BACKGROUND: The UNC5C rs3846455(G) allele has been linked to poor cognitive resilience against age-related neuropathologies, but this association remains to be replicated, and the allele’s effect on hippocampal neurodegeneration needs to be examined. OBJECTIVE: To further validate the association be...

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Publicado no:J Alzheimers Dis
Main Authors: Yang, Hyun-Sik, Chhatwal, Jasmeer P., Xu, Jishu, White, Charles C., Hanseeuw, Bernard, Rabin, Jennifer S., Papp, Kathryn V., Buckley, Rachel F., Schultz, Aaron P., Properzi, Michael J., Gatchel, Jennifer R., Amariglio, Rebecca E., Donovan, Nancy J., Mormino, Elizabeth C., Hedden, Trey, Marshall, Gad A., Rentz, Dorene M., Johnson, Keith A., De Jager, Philip L., Sperling, Reisa A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571137/
https://ncbi.nlm.nih.gov/pubmed/30883345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180788
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