The effects of PTPN2 loss on cell signalling and clinical outcome in relation to breast cancer subtype

PURPOSE: The protein tyrosine phosphatase PTPN2 dephosphorylates several tyrosine kinases in cancer-related signalling pathways and is thought to be a tumour suppressor. As PTPN2 is not frequently studied in breast cancer, we aimed to explore the role of PTPN2 and the effects of its loss in breast c...

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Bibliographic Details
Published in:J Cancer Res Clin Oncol
Main Authors: Veenstra, Cynthia, Karlsson, Elin, Mirwani, Sanam Mirwani, Nordenskjöld, Bo, Fornander, Tommy, Pérez-Tenorio, Gizeh, Stål, Olle
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2019
Subjects:
Original Article – Clinical Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571101/
https://ncbi.nlm.nih.gov/pubmed/31025094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-019-02918-y
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