IP6K2 predicts favorable clinical outcome of primary breast cancer

The inositol hexakisphosphate kinase (IP6K) 1 and 2 genes are localized at 3p21.31, a highly altered gene-dense chromosomal region in cancer. The IP6Ks convert IP6 to IP7, which inhibits activation of the tumor-promoting PI3K/Akt/mTOR signaling pathway. IP6K2 has been suggested to be involved in p53...

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Detalhes bibliográficos
Publicado no:Mol Clin Oncol
Main Authors: Sandström, Josefine, Balian, Alien, Lockowandt, Rebecca, Fornander, Tommy, Nordenskjöld, Bo, Lindström, Linda, Pérez-Tenorio, Gizeh, Stål, Olle
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7976380/
https://ncbi.nlm.nih.gov/pubmed/33767863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2021.2256
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