Label-free quantitative proteomics identifies transforming growth factor β1 (TGF-β1) as an inhibitor of adipogenic transformation in OP9-DL1 cells and primary thymic stromal cells

BACKGROUND: Adipocyte accumulation is a predominant feature of age-related thymic involution, but the mechanisms responsible for thymic adipogenesis remain to be elucidated. The aim of this study was to identify key regulators in thymic adipogenesis. We used rosiglitazone, a potent peroxisome prolif...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Biosci
Auteurs principaux: Tan, Jianxin, Wang, Yajun, Wang, Siliang, Wu, Simeng, Yuan, Zhe, Zhu, Xike
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570845/
https://ncbi.nlm.nih.gov/pubmed/31249661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-019-0311-1
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