Notch1 Inhibits Rosiglitazone-Induced Adipogenic Differentiation in Primary Thymic Stromal Cells

Adipocyte deposition is believed to be a primary characteristic of age-related thymic involution. Herein, we cultured primary thymic stromal cells (TSCs), used rosiglitazone, a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist, to induce adipogenic differentiation, and investigated...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Wang, Yajun, Tan, Jianxin, Du, Hongmei, Liu, Xue, Wang, Siliang, Wu, Simeng, Yuan, Zhe, Zhu, Xike
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240707/
https://ncbi.nlm.nih.gov/pubmed/30483127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01284
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