TGF-β signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution

The thymus constitutes the primary lymphoid organ responsible for the generation of naive T cells. Its stromal compartment is largely composed of a scaffold of different subsets of epithelial cells that provide soluble and membrane-bound molecules essential for thymocyte maturation and selection. Wi...

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Autors principals: Hauri-Hohl, Mathias M., Zuklys, Saulius, Keller, Marcel P., Jeker, Lukas T., Barthlott, Thomas, Moon, Anne M., Roes, Jürgen, Holländer, Georg A.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2008
Matèries:
Immunobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481556/
https://ncbi.nlm.nih.gov/pubmed/18474727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-10-115618
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