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Promoter engineering enables overproduction of foreign proteins from a single copy expression cassette in Bacillus subtilis

BACKGROUND: Bacillus subtilis is developed to be an attractive expression host to produce both secreted and cytoplasmic proteins owing to its prominent biological characteristics. Chromosomal integration is a stable expression strategy while the expression level is not ideal compared with plasmid ex...

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Dettagli Bibliografici
Pubblicato in:Microb Cell Fact
Autori principali: Zhou, Chaoyang, Ye, Bin, Cheng, Shan, Zhao, Leizhen, Liu, Yuanxin, Jiang, Jiandong, Yan, Xin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570832/
https://ncbi.nlm.nih.gov/pubmed/31200722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1159-0
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