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Promoter engineering enables overproduction of foreign proteins from a single copy expression cassette in Bacillus subtilis
BACKGROUND: Bacillus subtilis is developed to be an attractive expression host to produce both secreted and cytoplasmic proteins owing to its prominent biological characteristics. Chromosomal integration is a stable expression strategy while the expression level is not ideal compared with plasmid ex...
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發表在: | Microb Cell Fact |
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Main Authors: | , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
BioMed Central
2019
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6570832/ https://ncbi.nlm.nih.gov/pubmed/31200722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1159-0 |
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