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Promoter engineering enables overproduction of foreign proteins from a single copy expression cassette in Bacillus subtilis

Abstract Background Bacillus subtilis is developed to be an attractive expression host to produce both secreted and cytoplasmic proteins owing to its prominent biological characteristics. Chromosomal integration is a stable expression strategy while the expression level is not ideal compared with pl...

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Main Authors: Chaoyang Zhou, Bin Ye, Shan Cheng, Leizhen Zhao, Yuanxin Liu, Jiandong Jiang, Xin Yan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-06-01
Colecção:Microbial Cell Factories
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Acesso em linha:http://link.springer.com/article/10.1186/s12934-019-1159-0
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