η-Secretase processing of APP inhibits neuronal activity in the hippocampus

Alzheimer's disease (AD) is characterized by the accumulation of amyloid plaques, which are predominantly composed of amyloid β-peptide (Aβ)1. Two principal physiological pathways either prevent or promote Aβ generation from its precursor (amyloid precursor protein; APP) in a competitive manner...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nature
Main Authors: Willem, Michael, Tahirovic, Sabina, Busche, Marc Aurel, Ovsepian, Saak V., Chafai, Magda, Kootar, Scherazad, Hornburg, Daniel, Evans, Lewis D.B., Moore, Steven, Daria, Anna, Hampel, Heike, Müller, Veronika, Giudici, Camilla, Nuscher, Brigitte, Wenninger-Weinzierl, Andrea, Kremmer, Elisabeth, Heneka, Michael T., Thal, Dietmar R., Giedraitis, Vilmantas, Lannfelt, Lars, Müller, Ulrike, Livesey, Frederick J., Meissner, Felix, Herms, Jochen, Konnerth, Arthur, Marie, Hélène, Haass, Christian
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570618/
https://ncbi.nlm.nih.gov/pubmed/26322584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14864
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker