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Cholinergic neurons—keeping check on amyloid β in the cerebral cortex

The physiological relevance of p75 neurotrophin receptor-mediated internalization of ligands with no apparent trophic functions by nerve cells remains unclear. Herein, we propose a homeostatic role for this in clearance of amyloid β (Aβ) in the brain. We hypothesize that uptake of Aβ in conjunction...

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Detalhes bibliográficos
Main Authors: Ovsepian, Saak V., Herms, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858826/
https://ncbi.nlm.nih.gov/pubmed/24376398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00252
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