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Opiate antagonist nalmefene improves intracellular free Mg2+, bioenergetic state, and neurologic outcome following traumatic brain injury in rats

Treatment of CNS trauma with the opiate antagonist naloxone improves outcome, though the mechanisms of action remain speculative. Nalmefene is another opiate-receptor antagonist, but it has substantially greater potency and duration of action than naloxone. It also has increased activity at kappa op...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Vink, R, McIntosh, TK, Rhomhanyi, R, Faden, AI
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570099/
https://ncbi.nlm.nih.gov/pubmed/2230942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-11-03524.1990
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