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In vivo characterization of the opioid antagonist nalmefene in mice

AIMS: The current study assessed the in vivo antagonist properties of nalmefene using procedures previously used to characterize the opioid antagonists naloxone, naltrexone, 6β-naltrexol and nalbuphine. MAIN METHODS: ICR mice were used to generate antagonist dose-response curves with intraperitoneal...

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Bibliografiske detaljer
Main Authors: Osborn, Melissa D., Lowery, John J., Skorput, Alex G.J., Giuvelis, Denise, Bilsky, Edward J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848904/
https://ncbi.nlm.nih.gov/pubmed/20159022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2010.02.013
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