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Allosteric modulation by benzodiazepine receptor ligands of the GABAA receptor channel expressed in Xenopus oocytes

Chick brain mRNA was isolated and injected into Xenopus oocytes. This led to the expression in the surface membrane of functional GABA- activated channels with properties reminiscent of vertebrate GABAA channels. The GABA-induced current was analyzed quantitatively under voltage-clamp conditions. Pi...

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Pubblicato in:J Neurosci
Autori principali: Sigel, E, Baur, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1988
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6569358/
https://ncbi.nlm.nih.gov/pubmed/2448430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.08-01-00289.1988
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