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Deacylcynaropicrin Inhibits RANKL-Induced Osteoclastogenesis by Inhibiting NF-κB and MAPK and Promoting M2 Polarization of Macrophages

Inflammation can promote the maturity of osteoclasts and bone resorption in many bone disease such as osteoporosis and arthritis. Here, we aimed to investigate the inhibitory effects of deacylcynaropicrin (DAC) on osteoclastogenesis and bone resorption induced by RANKL. Bone-marrow-derived macrophag...

詳細記述

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書誌詳細
出版年:Front Pharmacol
主要な著者: Li, Zhikun, Zhu, Xiaodong, Xu, Ruijun, Wang, Yi, Hu, Ruixi, Xu, Wei
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567936/
https://ncbi.nlm.nih.gov/pubmed/31231214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00599
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