Tyloxapol inhibits RANKL-stimulated osteoclastogenesis and ovariectomized-induced bone loss by restraining NF-κB and MAPK activation

OBJECTIVE: Tyloxapol is a non-ionic surfactant with diverse pharmacological effects including anti-inflammatory, anti-malignant tumor and antioxidant activities. However, the effect of tyloxapol on osteoclastogenesis has not been elucidated. In this study, we intended to clarify the effect of tyloxa...

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Detalhes bibliográficos
Publicado no:J Orthop Translat
Main Authors: Guo, Wen, Li, Haijun, Lou, Yan, Zhang, Yue, Wang, Jia, Qian, Ming, Wei, Haifeng, Xiao, Jianru, Xu, Youjia
Formato: Artigo
Idioma:Inglês
Publicado em: Chinese Speaking Orthopaedic Society 2021
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063697/
https://ncbi.nlm.nih.gov/pubmed/33981577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jot.2021.01.005
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