Mesenchymal stem cells alleviate hypoxia-induced oxidative stress and enhance the pro-survival pathways in porcine islets

Islet transplantation is a promising treatment for selected patients with type 1 diabetes mellitus (T1DM). Hypoxia and oxidative stress are major causes of damage to transplanted islets. Mesenchymal stem cells (MSCs) have been shown to enhance cell survival mainly through paracrine secretion. Howeve...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Exp Biol Med (Maywood)
Päätekijät: Tan, Yixiong, Nie, Wei, Chen, Cheng, He, Xuesong, Xu, Yuzhi, Ma, Xiaoqian, Zhang, Juan, Tan, Mengqun, Rong, Pengfei, Wang, Wei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: SAGE Publications 2019
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567589/
https://ncbi.nlm.nih.gov/pubmed/31042075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219844472
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