Mesenchymal stem cells alleviate hypoxia-induced oxidative stress and enhance the pro-survival pathways in porcine islets

Islet transplantation is a promising treatment for selected patients with type 1 diabetes mellitus (T1DM). Hypoxia and oxidative stress are major causes of damage to transplanted islets. Mesenchymal stem cells (MSCs) have been shown to enhance cell survival mainly through paracrine secretion. Howeve...

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Bibliografiske detaljer
Udgivet i:Exp Biol Med (Maywood)
Main Authors: Tan, Yixiong, Nie, Wei, Chen, Cheng, He, Xuesong, Xu, Yuzhi, Ma, Xiaoqian, Zhang, Juan, Tan, Mengqun, Rong, Pengfei, Wang, Wei
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2019
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567589/
https://ncbi.nlm.nih.gov/pubmed/31042075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219844472
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