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The PinX1/NPM interaction associates with hTERT in early-S phase and facilitates telomerase activation
BACKGROUND: Telomere maintenance is an important factor in tumorigenesis. PinX1 is a potent telomerase regulator which also involves in telomerase loading to telomeres. Nucleophosmin (NPM) can partially attenuate PinX1 inhibition of telomerase activity and NPM loading to hTERT requires PinX1. Howeve...
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| Publicado en: | Cell Biosci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6567508/ https://ncbi.nlm.nih.gov/pubmed/31210926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-019-0306-y |
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