Differences in Liver TFAM Binding to mtDNA and mtDNA Damage between Aged and Extremely Aged Rats

While mitochondrial dysfunction is acknowledged as a major feature of aging, much less is known about the role of mitochondria in extended longevity. Livers from aged (28-month-old) and extremely aged (32-month-old) rats were analyzed for citrate synthase activity, mitochondrial transcription factor...

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Udgivet i:Int J Mol Sci
Main Authors: Chimienti, Guglielmina, Picca, Anna, Fracasso, Flavio, Marzetti, Emanuele, Calvani, Riccardo, Leeuwenburgh, Christiaan, Russo, Francesco, Lezza, Angela Maria Serena, Pesce, Vito
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566948/
https://ncbi.nlm.nih.gov/pubmed/31137890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102601
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