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Multiple Active States and Oligomerization of CCR5 Revealed by Functional Properties of Monoclonal Antibodies

CC-chemokine receptor 5 (CCR5) is the principal coreceptor for macrophage-tropic strains of human immunodeficiency virus type 1 (HIV-1). We have generated a set of anti-CCR5 monoclonal antibodies and characterized them in terms of epitope recognition, competition with chemokine binding, receptor act...

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Udgivet i:Mol Biol Cell
Principais autores: Blanpain, Cédric, Vanderwinden, Jean-Marie, Cihak, Josef, Wittamer, Valérie, Le Poul, Emmanuel, Issafras, Hassan, Stangassinger, Manfred, Vassart, Gilbert, Marullo, Stefano, Schloō̈ndorff, Detlef, Parmentier, Marc, Mack, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC65662/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11854425/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.01-03-0129
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