Multiple Active States and Oligomerization of CCR5 Revealed by Functional Properties of Monoclonal Antibodies

CC-chemokine receptor 5 (CCR5) is the principal coreceptor for macrophage-tropic strains of human immunodeficiency virus type 1 (HIV-1). We have generated a set of anti-CCR5 monoclonal antibodies and characterized them in terms of epitope recognition, competition with chemokine binding, receptor act...

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Detalhes bibliográficos
Main Authors: Blanpain, Cédric, Vanderwinden, Jean-Marie, Cihak, Josef, Wittamer, Valérie, Le Poul, Emmanuel, Issafras, Hassan, Stangassinger, Manfred, Vassart, Gilbert, Marullo, Stefano, Schloō̈ndorff, Detlef, Parmentier, Marc, Mack, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC65662/
https://ncbi.nlm.nih.gov/pubmed/11854425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-03-0129
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