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Synaptotagmin 5 regulates calcium-dependent Weibel-Palade body exocytosis in human endothelial cells

Elevations of intracellular free Ca(2+) concentration ([Ca(2+)](i)) are a potent trigger for Weibel-Palade body (WPB) exocytosis and secretion of Von Willebrand factor (VWF) from endothelial cells, however, the identity of WPB-associated Ca(2+)-sensors involved in transducing acute increases in [Ca(...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Lenzi, Camille, Stevens, Jennifer, Osborn, Daniel, Hannah, Matthew J., Bierings, Ruben, Carter, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565431/
https://ncbi.nlm.nih.gov/pubmed/30659119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.221952
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