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Characterisation of Weibel–Palade body fusion by amperometry in endothelial cells reveals fusion pore dynamics and the effect of cholesterol on exocytosis

Regulated secretion from endothelial cells is mediated by Weibel–Palade body (WPB) exocytosis. Plasma membrane cholesterol is implicated in regulating secretory granule exocytosis and fusion pore dynamics; however, its role in modulating WPB exocytosis is not clear. To address this we combined high-...

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Autori principali: Cookson, Emma A., Conte, Ianina L., Dempster, John, Hannah, Matthew J., Carter, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843139/
https://ncbi.nlm.nih.gov/pubmed/24127569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.138438
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