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Reductively-labile sulfonate ester protecting groups that are rapidly cleaved by physiological glutathione
Sulfonates are frequently used to endow water solubility on hydrophobic molecules, but the repertoire of sulfonate protecting groups remains limited. Here we describe the first sulfonate esters that can be unmasked by the mild reducing conditions found in live mammalian cells. Self-immolative cleava...
Shranjeno v:
| izdano v: | Org Biomol Chem |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6563934/ https://ncbi.nlm.nih.gov/pubmed/28116407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob00063d |
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