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Understanding Acid Lability of Cysteine Protecting Groups

Cys-disulfide bonds contribute to the stabilization of peptide and protein structures. The synthesis of these molecules requires a proper protection of Cys residues, which is crucial to prevent side-reactions and also to achieve the correct Cys connectivity. Here we undertook a mechanistic study of...

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Publicado en:Molecules
Autores principales: Ramos-Tomillero, Iván, Mendive-Tapia, Lorena, Góngora-Benítez, Miriam, Nicolás, Ernesto, Tulla-Puche, Judit, Albericio, Fernando
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270164/
https://ncbi.nlm.nih.gov/pubmed/23648593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18055155
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