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Current clinical use of polygenic scores will risk exacerbating health disparities
Polygenic risk scores (PRS) are poised to improve biomedical outcomes via precision medicine. However, the major ethical and scientific challenge surrounding clinical implementation is that they are many-fold more accurate in European ancestry individuals than others. This disparity is an inescapabl...
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| Publié dans: | Nat Genet |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6563838/ https://ncbi.nlm.nih.gov/pubmed/30926966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0379-x |
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