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Current clinical use of polygenic scores will risk exacerbating health disparities
Polygenic risk scores (PRS) are poised to improve biomedical outcomes via precision medicine. However, the major ethical and scientific challenge surrounding clinical implementation is that they are many-fold more accurate in European ancestry individuals than others. This disparity is an inescapabl...
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| Publicado en: | Nat Genet |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6563838/ https://ncbi.nlm.nih.gov/pubmed/30926966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0379-x |
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