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Functional genetic variants revealed by massively parallel precise genome editing
A major challenge in genetics is to identify genetic variants driving natural phenotypic variation. However, current methods of genetic mapping have limited resolution. To address this gap, we developed a CRISPR-Cas9-based high-throughput genome editing approach that can introduce thousands of speci...
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| Veröffentlicht in: | Cell |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6563827/ https://ncbi.nlm.nih.gov/pubmed/30245013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.08.057 |
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