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Heterogeneity and Architecture of Pathological Prion Protein Assemblies: Time to Revisit the Molecular Basis of the Prion Replication Process?
Prions are proteinaceous infectious agents responsible for a range of neurodegenerative diseases in animals and humans. Prion particles are assemblies formed from a misfolded, β-sheet rich, aggregation-prone isoform (PrP(Sc)) of the host-encoded cellular prion protein (PrP(C)). Prions replicate by r...
Tallennettuna:
| Julkaisussa: | Viruses |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
MDPI
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6563208/ https://ncbi.nlm.nih.gov/pubmed/31083283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11050429 |
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